The bioavailability of nutrients from plant sources is dependent on intestinal absorptive capacity, which is linked to the environment, sanitation/hygiene and the intestinal microbiome: in turn, this will affect the success of nutritional interventions. In this program, new methods of estimating the bioavailability of nutrients in humans through intrinsic stable isotope labelling of plants will be developed, along with novel and sensitive human physiological studies of their efficacy through dynamic proteomics and other methods.
Specific experiments under this project:
Measurement of the digestibility and absorption of legume protein (chickpea, mungbean) using stable isotopes methods in humans.
Measuring Vitamin A stores after green leafy vegetables intake in adults.
Iron Bioavailability from germinated ragi in non-pregnant non-lactating Indian women.
Measurements of protein synthesis rates in human using dynamic proteomics with stable isotopes.