IMAGING NEEDLES: Deep tissue multi-modal molecular imaging needle-probes

This study aims to develop a guidance technology platform that has the potential to enhance various minimally invasive surgeries in resource-limited settings.  The core objective of the study is to develop comprehensive technologies that enable photoacoustic (PA) and ultrasound (US) imaging at tips of probes, to visualize tissues during surgeries.

Two specific prototypes will be developed for interstitial imaging and tissue characterization, with applications in radio-frequency (RF) ablation (Photoacoustic Needle – PAN which will be tested at SJRI, Bangalore during Year 3 & 4) and in neurosurgery (Ultrasound-Photoacoustic needle – USPAN which will be tested at NIMHANS, Bangalore).