This proposal views biodesign and bioengineering as the application of engineering tools and techniques to solve problems arising in biology and clinical medicine. It is a broad field: research in this discipline ranges from fundamental studies such as cellular mechanics to highly applied work such as the development of technology to assist rehabilitation of a patient. The proposed work is fundamentally interdisciplinary that integrates engineering, biology, and clinical practices. With the intent of having a direct impact on human health, it brings together researchers and clinicians to study a few focused topics in the biomedical field.
Four projects are listed under the DBT BBI Phase-II programme: These include
Project-1: Analysis of hemoglobin variants. Principle Investigator: Dr. Amit K Mandal, St. John’s Research Institute, Co-PI: Dr. Cecil Ross, St. John’s Medical College and Hospital
Project-2: Urinary and kidney tissue proteomics in Adult Nephrotic Syndrome, Principle Investigator: Dr. Limesh M, St. John’s Medical College and Hospital, Co-PI: Dr. Amit K Mandal, St. John’s Research Institute
Project-3: A Brain Function Index Apparatus to Objectively Evaluate Cognition using Neuro-physiological Metrics, Principle Investigator: Dr. Mahesh Jayachandra, St. John’s Research Institute, Co-PI: Dr. K. Srinivasan, St. John’s Research Institute
Project-4: Neuro-protective Intervention in a Realistic, Neurophysiological model of Stroke in Rats, Principle Investigator: Dr. Mahesh Jayachandra, St. John’s Research Institute, Co-PI: Dr. Amit K Mandal, St. John’s Research Institute