Cardiovascular Diseases

Introduction

The cardiovascular health activities are in response to the growing burden of these diseases due to the social, demographic, epidemiologic and health care transitions that have led to cardiovascular diseases being the number one cause of death in the country.

The activities are dedicated to:

  • Providing a platform for cardiovascular health research that is relevant to resource-limited settings
  • Focusing on key individual determinants (tobacco, diet, physical activity and psychological factors) as well as underlying social determinants (‘causes of causes’)
  • Providing a robust training environment that will foster a new generation of scholars engaged in cardiovascular research
  • Enhancing the translation and dissemination of research findings among vulnerable populations
  • Achieving a reputation for excellence in cardiovascular health research

Sl No. Project Title Project Lead Year
1 Librexia AF is a randomized, double-blind, double-dummy, parallel group, active-controlled study to evaluate the efficacy and safety of milvexian versus apixaban in participants with atrial fibrillation. National Leader: Dr Denis Xavier Year of initiation: July 2024
2 SUPPORT -Strategies for non-communicable disease prevention in select populations in different regions of India PI- Dr Denis Xavier Co-I- Dr. Deepa Srinivasan, Dr. Aakanksha Singh, Dr. Ryan Fernandez, Ms. Freeda Year of initiation: 2023
3 Impact, cost-effectiveness, and sustainability of a synergistic, multipronged, customized, low-cost intervention package (IP) to reduce cardiovascular disease (CVD) burden among diverse populations across India (ICMR-CAR) PI : Dr Denis Xavier Year of Initiation : 2024
4 Improving glycemic control in urban primary care settings PI: Dr. Farah Fathima Co-I: Dr.Prem K. Mony 2024 - 2027
5 Prospective Global Platform to Evaluate and Enhance Cognitive and Functional Trajectories after Stroke (PROSPECT) PI- Dr. Denis Xavier Co-I- Dr. Atiya R Faruqui 2024
6 COLchicine and Thiamine in Heart Failure due to Ischemic Heart Disease (COLT-HF) PI- Dr Denis Xavier, Co-I- Dr Mangala Rao 2024
7 RADICAL PC1- Role of Androgen Deprivation Therapy In CArdiovascular Disease – A Longitudinal Prostate Cancer Study. RADICAL PC2- A RAndomizeD Intervention for CArdiovascular and Lifestyle Risk Factors in Prostate Cancer Patients. PI: Dr Denis Xavier, Co I: Dr Deepa S 2023
8 ENRICH-AF - EdoxabaN foR IntraCranial Hemorrhage survivors with Atrial Fibrillation PI: Dr. Denis Xavier, Co-I: Dr. Padmini Devi 2020
9 POISE-3 - Peri-Operative ISchemic Evaluation-3 PI: Dr Denis Xavier 2018 onwards
10 G-CHF - A global registry on demographics, socio-economic and clinical factors, aetiologies, pathophysiology, management and outcomes of heart failure Dr. Kiron Varghese, Dr. Denis Xavier, Dr. Deepak Kamath 2017