ACHIEVE -Aldosterone bloCkade for Health Improvement EValuation in End-stage renal disease

Details

a) Background:

A randomized placebo controlled trial to assess the safety and efficacy of spironolactone on cardiovascular outcomes among patients with end-stage renal disease

b) Objectives:

  • Primary:  To determine if spironolactone reduces cardiac morbidity and mortality for patients treated with chronic dialysis.
  • Secondary:  To assess the safety and other efficacy of spironolactone in patients treated with chronic dialysis

c) Sample size:

Global  - 2750 / India - 500

d) Study update:

  • Global – 2,205- Run in and 1,577 –Randomized
  • In India-534- Run in and 393- Randomised

Updated as on: 27 Apr 2022

سایت بازی انفجار