Projects

Sl No. Project Title Project Lead Year
1 Librexia AF is a randomized, double-blind, double-dummy, parallel group, active-controlled study to evaluate the efficacy and safety of milvexian versus apixaban in participants with atrial fibrillation. National Leader: Dr Denis Xavier Year of initiation: July 2024
2 Prevalence, Risk factors, COnsequences and opporTunities for prevention of falls in Elderly with select Chronic condiTions (PROTECT 2): A Mixed Methods Study PI- Dr. Denis Xavier, Co-I: Dr. Atiya Faruqui, Dr. Arvind Kasturi, Dr. Jonita Furtado, Dr. Pretesh R Year of initiation: 2025
3 Zilebesiran Cardiovascular Outcomes Trial (ZCVOT) National Leaders and SC : Dr Denis Xavier Year of initiation: 2025
4 Presentation, tReatments, challenges and Opportunities for optimal Treatments in the Elderly with select Chronic condiTions (PROTECT) Study PI: Dr. Atiya R. Faruqui, Co-I: Dr. Arvind Kasthuri, Dr. Denis Xavier, Dr. Jonita, Dr. Pretesh Kiran Year of initiation: 2024
5 Development and validation of a deprescribing tool relevant to the Indian context and evaluation of its effectiveness in reducing inappropriate polypharmacy in the elderly (ICMR-SRUM-NTF) PI: Dr. Atiya R. Faruqui, Co-I: Dr. Geetha Francis, Dr. Pretesh Kiran Year of initiation: 2023
6 Pregnancy outcomes and it’s determinants at a tribal hospital in south India– A prospective cohort study (PREDICT) PI- Dr. Denis Xavier, Co-I : Dr. Padmini Devi , Dr Deepa. S, Dr. Ryan Fernandez Year of initiation: 2022
7 A Phase 3, Randomized, Double-Blind, Placebo-controlled, Event-driven Study to Demonstrate the Efficacy and Safety of an Oral Factor XIa Inhibitor, after a Recent Acute Coronary Syndrome (Milvexian ACS) National Leader- Dr Denis Xavier Year of initiation: 30th Oct 2023
8 COLchicine and Thiamine in Heart Failure due to Ischemic Heart Disease (COLT-HF) PI- Dr Denis Xavier, Co-I- Dr Mangala Rao Year of Initiation : 2024
9 Impact, cost-effectiveness, and sustainability of a synergistic, multipronged, customized, low-cost intervention package (IP) to reduce cardiovascular disease (CVD) burden among diverse populations across India (ICMR-CAR) PI : Dr Denis Xavier Year of Initiation : 2024
10 Prospective Global Platform to Evaluate and Enhance Cognitive and Functional Trajectories after Stroke (PROSPECT) PI- Dr. Denis Xavier Co-I- Dr. Atiya R Faruqui Year of Initiation : 2024
11 RADICAL PC1- Role of Androgen Deprivation Therapy In CArdiovascular Disease – A Longitudinal Prostate Cancer Study. RADICAL PC2- A RAndomizeD Intervention for CArdiovascular and Lifestyle Risk Factors in Prostate Cancer Patients. PI: Dr Denis Xavier, Co I: Dr Deepa S Year of Initiation : 2023
12 ENRICH-AF - EdoxabaN foR IntraCranial Hemorrhage survivors with Atrial Fibrillation PI: Dr. Denis Xavier, Co-I: Dr. Padmini Devi Year of Initiation : 2020
13 ACHIEVE -Aldosterone bloCkade for Health Improvement EValuation in End-stage renal disease PI: Dr. Denis Xavier, Co-I: Dr.Atiya Faruqui 2019
14 POISE-3 - Peri-Operative ISchemic Evaluation-3 PI: Dr Denis Xavier 2018 onwards
Sl No. Project Title Project Lead Year