An ongoing Indian Council of Medical Research (ICMR) funded study at St. John's Medical College Hospital, Bangalore, India, is developing a behavioural measure to track children at risk from 9 to 18 months. It would be aimed to follow up these children till their 60 months of age with various measures to study the genetic and neurobehavioral signatures of ASD. We also intend using machine learning methods to develop/modify screening tools and diagnostic measures for use across the country where professional resources are scarce.