De novo lipogenesis in adiposity and glycaemic control: Epigenetic mechanisms and associated metabolite profiles (Funded by: DBT / Wellcome Trust India Alliance)

In India, a country undergoing rapid economic and sociodemographic transition, type 2 diabetes has taken epidemic proportions, directly leading to years of life lost to ill-health and early death and wreaking economic havoc on communities.

The proposed research will examine the following:
1. How fat storage in the adipose (the fat depots of our body) is controlled?
2. Do problems in fat storage in the adipose associated with diet and other lifestyle factors lead to development of type 2 diabetes?

Findings from the current study will guide the exploration of new preventive and therapeutic approaches that target the adipose.

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