Infectious Diseases

Introduction

The tuberculosis (TB) epidemiological studies were conducted at the Palamaner field site in Chittoor District, Andhra Pradesh, set up under a programme approved by the Ministry of Health Screening Committee, Government of India. The studies were funded by the Aeras Global TB Vaccine Foundation, USA, and the Research Council of Norway. Three large cohort studies assessed cumulative incidence of TB in 1) newborns followed for 2 years, 2) adolescents aged 12 to <18 years followed for 2 years and 3) household contacts of smear positive TB index cases followed for a year. Apart from epidemiological analyses, the studies will also contribute to the evaluation of biomarkers in latent TB infection and TB disease.

Sl No. Title Authors Journal Name Publication Year
1 Tuberculosis notification in a private tertiary care teaching hospital in South India: a mixed-methods study Siddaiah A, Ahmed MN, Kumar AMV, D'Souza G, Wilkinson E, Maung TM, Rodrigues R BMJ Open 2019
2 Evidence for highly variable, region-specific patterns of T-cell epitope mutations accumulating in Mycobacterium tuberculosis strains Ramaiah A, Nayak S, Rakshit S, Manson AL, Abeel T, Shanmugam S, Sahoo PN, John AJUK, Sundaramurthi JC, Narayanan S, D'Souza G, von Hoegen P, Ottenhoff THM, Swaminathan S, Earl AM, Vyakarnam A Front Immunol 2019
3 Measuring adherence to antiretroviral therapy via hair concentrations in India Gandhi M, Devi S, Bacchetti P, Chandy S, Heylen E, Phung N, Kuncze K, Okochi H, Kumar R, Kurpad AV, Ekstrand ML J Acquir Immune Defic Syndr 2019
4 Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation D'Souza RR, Gopalan BP, Rajnala N, Phetsouphanh C, Shet A HIV Med 2019
5 Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India Gunisetty S, Nayak K, Chandra Rai R, Chawla Y, Reddy ES, Aggarwal C, Maheshwari D, Panda H, Ansari NA, Singh P, Kaur M, Dixit K, Sharma P, Bhatnagar P, Priyamvada L, Bhaumik SK, Ahamed SF, Vivek R, Ray P, Shet A, Coshic P, Lodha R, Kabra SK, Afroze D, Yousuf A, Ahmed R, Murali-Krishna K, Chandele A Int J Infect Dis 2019
6 Emergence of new genotypes and lineages of dengue viruses during the 2012-15 epidemics in southern India Ahamed SF, Rosario V, Britto C, Dias M, Nayak K, Chandele A, Kaja MK, Shet A Int J Infect Dis 2019
7 Viral evolution in the cell-associated HIV-1 DNA during early ART can lead to drug resistance and virological failure in children Gopalan BP, D'Souza RR, Rajnala N, Arumugam K, Dias M, Ranga U, Shet A J Med Virol 2019
8 Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy Hameed PS, Bharatham N, Katagihallimath N, Sharma S, Nandishaiah R, Shanbhag AP, Thomas T, Narjari R, Sarma M, Bhowmik P, Amar P, Ravishankar R, Jayaraman R, Muthan K, Subbiah R, Ramachandran V, Balasubramanian V, Datta S Sci Rep 2018
9 Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis Ahmed A, Adiga V, Nayak S, Uday Kumar JAJ, Dhar C, Sahoo PN, Sundararaj BK, Souza GD, Vyakarnam A PLoS Pathog 2018
10 Seasonal prevalence of antibiotic-resistant bacteria in the river Mula-Mutha, India Dhawde R, Macaden R, Ghadge A, Birdi T Environ Monit Assess 2018
11 Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: a cluster randomised trial in Indian neonates vaccinated with BCG Jenum S, Sumithra S, Nelson J, Christian R, Anneke C H, Vicky C, Esther L, Mark DT, Harleen M S G, Mario V BMJ Open Respir Res 2018
12 High Abundance of genus Prevotella in the gut of perinatally HIV-infected children is associated with IP-10 levels despite therapy Kaur US, Shet A, Rajnala N, Gopalan BP, Moar P, D H, Singh BP, Chaturvedi R, Tandon R Sci Rep 2018
13 Development of a Novel Tablet-based Approach to Reduce HIV Stigma among Healthcare Staff in India Radhakrishna K, Dass D, Raj T, Rakesh D, Kishore R, Srinivasan K, Nyblade L, Ekstrand-Abueg M, Ekstrand ML Perspect Health Inf Manag 2017
14 Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children Gjøen JE, Jenum S, Sivakumaran D, Mukherjee A, Macaden R, Kabra SK, Lodha R, Ottenhoff THM, Haks MC, Doherty TM, Ritz C, Grewal HMS Sci Rep 2017
15 Enhancing the sensitivity of Dengue virus serotype detection by RT-PCR among infected children in India Ahamed SF, Vivek R, Kotabagi S, Nayak K, Chandele A, Kaja MK, Shet A J Virol Methods 2017