Brief Description about the Project
This project is to develop a novel point-of-care device that non-invasively estimates blood rifampicin and bilirubin levels simultaneously, enabling early identification of hepatotoxicity and supporting tailored anti-tubercular therapy in community and programmatic settings. The prototype will be calibrated against gold-standard methods using data from individuals taking rifampicin and patients with hyperbilirubinemia. The expected outcome is a robust, affordable tool for point-of-care therapeutic drug monitoring that can improve cure rates, reduce treatment dropouts, and lower the risk of antimicrobial resistance through dose optimization. Concurrent bilirubin monitoring will facilitate early detection of drug-induced hepatotoxicity, further enhancing safety. Integration of this device into India’s National TB Elimination Program and comparable global initiatives could meaningfully improve treatment outcomes and inform future policy decisions.
Project Research Scientist I (non-medical)
No. of Vacancy: Two
Preferred Qualifications:MBBS, or Graduate degree in a relevant medical or clinical field with Additional qualifications such as MPH, PhD, or specialization in Epidemiology, Public Health, or Clinical Research are desirable.
Experience:
1. Minimum 3 years of experience in clinical research, medical device validation, or public health studies.
2. Experience in working on medical device research, infectious diseases, or community-based healthcare projects is preferred.
3. Proficiency in data analysis software (SPSS, R, STATA, NVivo, or similar).
4. Experience in qualitative and quantitative research methodologies, data management, and literature review.
5. Prior experience in manuscript writing and research grant applications is desirable.
6. Familiarity with ethics approval processes and Good Clinical Practice (GCP) guidelines.
7. Experience in collaborating with national and international research organizations is an advantage.
Preferred Language:
Age Limit: 35 Years
Location: Bangalore
Salary: Rs. 72,800/- per month
Roles & Responsibilities:
1. Assist in the design, implementation, and management of research activities related to the Project.
2. Support data collection, management, and preliminary analysis for the evaluation of the screenless ultrasound device.
3. Work closely with the Project Co Investigators to coordinate validation studies involving 60 TB patients.
4. Collaborate with biomedical engineers, data scientists, and healthcare professionals to refine device features and research methodologies.
5. Develop survey instruments, interview guides, and research tools for stakeholder consultations, including hospital administrators and healthcare workers.
6. Conduct literature reviews and assist in drafting research papers, reports, and presentations.
7. Monitor project timelines, data quality, and regulatory compliance under the guidance of the medical research scientist.
8. Assist in grant writing and proposal development for securing additional funding.
9. Organize and participate in stakeholder meetings, workshops, and training sessions for research staff and healthcare workers.
10. Support field teams in troubleshooting data collection challenges and ensure adherence to ethical research practices.
11. Analyze qualitative and quantitative data using quantitative and qualitative analysis software and visualization tools.
12. Maintain detailed project documentation, including research protocols, consent forms, and ethics committee submissions.
13. Travel to project sites for field validation and stakeholder studies.
Interested candidates may send their Resume to:
The Principal Investigator
ICMR-FIW-TB-TDM Project
SJRI
To Apply: E-mail cover letter and curriculum vitae with 3 references (names and email addresses / phone numbers) by on or before 21st February 2026 to verghese.t@sjri.res.in & cc to hr@sjri.res.in
For more information, please visit our website www.sjri.res.in