Design and rationale of CURRENT-OASIS 7: a randomized, 2 x 2 factorial trial evaluating optimal dosing strategies for clopidogrel and aspirin in patients with ST and non-ST-elevation acute coronary syndromes managed with an early invasive strategy

Authors : Mehta SR, Bassand JP, , Yusuf S; CURRENT-OASIS 7 Steering Committee

Publication Year : 2008

Abstract :

To evaluate the efficacy and safety of (1) a higher loading and initial maintenance dose of clopidogrel compared with the standard-dose regimen and (2) high-dose ASA compared with low-dose ASA in patients with ST or non–ST-segment-elevation ACS managed with an early invasive strategy.

https://www.sciencedirect.com/science/article/pii/S0002870308006674