Authors : Pavel S Roshanov, Michael W Walsh, Amit X Garg, Meaghan Cuerden, Ngan N Lam, Ainslie M Hildebrand, *Denis Xavier*, Daniel I Sessler, PJ Devereaux, et al…
Publication Year : 2025
Background: Optimised use of kidney function information might improve cardiac risk prediction in noncardiac surgery.
Methods: In 35,815 patients from the VISION cohort study and 9219 patients from the POISE-2 trial who were 45 yr old
and underwent nonurgent inpatient noncardiac surgery, we examined (by age and sex) the association between
continuous nonlinear preoperative estimated glomerular filtration rate (eGFR) and the composite of myocardial injury
after noncardiac surgery, nonfatal cardiac arrest, or death owing to a cardiac cause within 30 days after surgery. We
estimated contributions of predictive information, C-statistic, and net benefit from eGFR and other common patient and
surgical characteristics to large multivariable models.
https://www.bjanaesthesia.org.uk/action/showPdf?pii=S0007-0912%2824%2900702-5