Publications

Sl No. Title Authors Journal Name Publication Year
31 Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease Johannes FE Mann, Philipp Joseph, Peggy Gao, *Prem Pais*, Jessica Tyrwhitt, *Denis Xavier*, Tony Dans, Patricio Lopez Jaramillo, Habib Gamra, Salim Yusuf. Kidney International 2022
32 Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury: A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial. Amit X Garg, Meaghan Cuerden, Richard Whitlock, Maria Wittmann, *Denis Xavier*, PJ Devereaux, Hector Aguado, Mohammed Amir, Emilie P Belley-Cote, Keyur Bhatt, Bruce M Biccard Michael McGillion, William McIntyre, Christian Meyhoff, Sandra Ofori, Thomas Painter, Pilar Paniagua, Chirag Parikh, Joel Parlow, Ameen Patel, Carisi Polanczyk, Toby Richards, Pavel Roshanov, et al. Canadian Journal of Kidney Health and Disease 2022
33 HbA1c Reduction in Dulaglutide-Treated Patients Irrespective of Duration of Diabetes, Microvascular Disease, and BMI: A Post Hoc Analysis From the REWIND Trial Anita YM Kwan, Hertzel C Gerstein, Jan Basile, *Denis Xavier*, Juan M Maldonado, Sohini Raha, Manige Konig Diabetes Care 2022
34 Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study Smyth A, O’Donnell M, Hankey GJ, Rangarajan S, Lopez-Jaramillo P, *Xavier D*, Zhang H, Canavan M, Damasceno A, Langhorne P, Avezum A, INTERSTROKE investigators European Heart Journal 2022
35 The Anti-Coronavirus Therapy (ACT) trials: design, baseline characteristics, and challenges Eikelboom J, Rangarajan S, Jolly SS, Belley-Cote EP, *Prem Pais*, *Xavier D*, Whitlock R, Beresh H, Lewis G, Xu L, Chan N, Bangdiwala S, Diaz R, et all.. CJC open 2022
36 Tranexamic acid in patients undergoing noncardiac surgery PJ Devereaux, Maura Marcucci, *Denis Xavier*, Jessica Vincent, John Eikelboom, Jessica Spence, Toby Richards, Tomas VanHelder, William McIntyre, Gordon Guyatt, Salim Yusuf, Kate Leslie, et al… New England Journal of Medicine 2022
37 Effects of Aspirin in Primary Prevention of Cardiovascular (CV) Disease in People with Chronic Kidney Disease (CKD): Results of the TIPS3 Trial. Johannes FE Mann, Philip Joseph, Peggy Gao, *Prem Pais*, *Denis Xavier*, Tony Dans, Patricio Lopez Jaramillo, Habib Gamra, Jessica Tyrwhitt, Salim Yusuf MO201 Nephrology Dialysis Transplantation 2022
38 Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery Maura Marcucci, Thomas W Painter, David Conen, Kate Leslie, Vladimir V Lomivorotov, Daniel Sessler, Matthew TV Chan, Flavia K Borges, , *Denis Xavier*, Ingrid Copland, Jessica Vincent, Gordon Guyatt, Emily Belley-Cote, Jessica Spence, William McIntyre, Salim Yusuf, PJ Devereaux, Et al Trials 2022
39 A novel kidney disease index reflecting both the albumin-to-creatinine ratio and estimated glomerular filtration rate, predicted cardiovascular and kidney outcomes in type 2 diabetes Hertzel C Gerstein, Chinthanie Ramasundarahettige, Alvero Avezum, Jan Basile, Ignacio Conget, William C Cushman, Gilles R Dagenais, Edward Franek, Mark Lakshmanan, Fernando Lanas, Lawrence A Leiter, *Denis Xavier*, et al.. Cardiovascular diabetology 2022
40 Alcohol Intake as risk factor for Acute Stroke : The Interstroke Study Andrew Smyth, Martin O'Donnell, Sumathy Rangarajan, Graeme J Hankey, Shahram Oveisgharan, Michelle Canavan, Clodagh McDermott, *Denis Xavier*, Salim Yusuf, Peter Langhorne, INTERSTROKE Investigators, et al.. Neurology 2022
41 Vitamin D supplementation and adverse skeletal and non-skeletal outcomes in individuals at increased cardiovascular risk: results from the The International Polycap Study (TIPS)-3 randomized controlled trial P Joseph, *P Pais*, P Gao, K Teo, *D Xavier*, P Lopez-Jaramillo, K Yusoff, A Santoso, H Gamra, SH Talukder, C Christou, G Dagenais, J Tyrwhitt, J Bosch, A Dans, S Yusuf, International Polycap Study Investigators. Nutrition, Metabolism and Cardiovascular Diseases 2022
42 External applicability of the Effect of ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) trial: An analysis of patients with diabetes and coronary artery disease in the REduction of Atherothrombosis for Continued Health (REACH) registry. Abtan J, Bhatt DL, Elbez Y, Ducrocq G, Goto S, Smith SC Jr, Ohman EM, Eagle KA, Fox K, Harrington RA, Leiter LA, Mehta SR, Simon T, Petrov I, Sinnaeve PR, *Pais P*, Lev E, Bueno H, Wilson P, Steg PG, on behalf of the REACH Registry Investigators International Journal of Cardiology 2022
43 Dulaglutide and cardiovascular and heart failure outcomes in patients with and without heart failure: a post-hoc analysis from the REWIND randomized trial Branch KRH, Dagenais GR, Avezum A, Basile J, Conget I, Cushman WC, Jansky P, Lakshmanan M, Lanas F, Leiter LA, *Pais P*, Pogosova N, Raubenheimer PJ, Ryden L, Shaw JE, Sheu WHH, Temelkova-Kurktschiev T, Bethe MA, Gerstein HC, Chinthanie R & Probstfiel JL. European Journal of Heart Failure 2022
44 Association of Psychosocial Stress With Risk of Acute Stroke Catriona Reddin, Robert Murphy, Graeme J Hankey, Conor Judge, *Denis Xavier*, Annika Rosengren, John Ferguson, Salim Yusuf, Martin O’Donnell, Sumathy Rangaran, *Prem Pais*, Osamah Albaker, et al.. JAMA Network Open 2022
45 Role of Proxy Respondents in International Stroke Research: Experience of the INTERSTROKE Study Maria M Costello, Conor Judge, Catriona Reddin, Sumathy Rangarajan, Peter Langhorne, Hongye Zhang, Helle K Iversen, *Denis Xavier*, Andrew Smyth, Michelle D Canavan, Salim Yusuf, Martin J O’Donnell Neuroepidemiology 2022