Sequence and analysis of Non-tuberculous Mycobacteria

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The objective of the proposed analysis is to characterize NTM strains representing geographically diverse TB-endemic areas with high NTM prevalence. The availability of these well-characterized strains will help researchers better understand the NTM/TB disease dynamic and the impact of NTMs on TB vaccine trial results, particularly on a candidate vaccine’s immunogenicity and protective efficacy. Ancillary findings from adolescent and neonatal cohort studies conducted by Aeras to determine the incidence and prevalence of TB in Cambodia, India, Mozambique, South Africa, and Uganda included the prevalence and typing of NTM infections.

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