Cardiovascular Diseases

Introduction

The cardiovascular health activities are in response to the growing burden of these diseases due to the social, demographic, epidemiologic and health care transitions that have led to cardiovascular diseases being the number one cause of death in the country.

The activities are dedicated to:

  • Providing a platform for cardiovascular health research that is relevant to resource-limited settings
  • Focusing on key individual determinants (tobacco, diet, physical activity and psychological factors) as well as underlying social determinants (‘causes of causes’)
  • Providing a robust training environment that will foster a new generation of scholars engaged in cardiovascular research
  • Enhancing the translation and dissemination of research findings among vulnerable populations
  • Achieving a reputation for excellence in cardiovascular health research

Sl No. Project Title Project Lead Year
16 A randomized controlled trial of low-dose aspirin after initial anticoagulation to prevent the recurrence of venous thromboembolism - ASPIRE STUDY Dr. Prem Pais, Dr. Denis Xavier 2012
17 A pilot study for the Early Diagnosis & Prevention System (EDPS) Dr. Denis Xavier 2011
18 A Prospective Study of Practice Pattern and Outcome in Chronic Disease in an Urban Family Practices (FRIENDS) Dr. Denis Xavier, Dr. Atiya Faruqui 2010
19 An ongoing program (research, patient management strategies) to prevent & manage Cardiovascular diseases in India (AMEND Program). Dr. Denis Xavier, Dr. Padmini Devi, Dr. Atiya Faruqui, Dr. Mangala Rao 2010
20 A multi-centre, randomised, double-blind, placebo-controlled, clinical trial examining the efficacy and safety of multi-vitamin therapy in secondary stroke prevention (VITATOPS) Dr. Denis Xavier, Dr. Prem Pais 2009
21 Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) Comparing the Efficacy and Safety of Two Blinded Doses of Dabigatran Etexilate With Open Label Warfarin for the Prevention of Stroke and Systemic Embolism in Patients With Non-valvular Atrial Fibrillation: Prospective, Multi-centre, Parallel-group, Non-inferiority Trial (RE-LY Study) Dr. Prem Pais, Dr. Denis Xavier 2009
22 To determine the efficacy and safety of a POLYCAP versus its components in subjects with at least one Cardiovascular risk factor (POLYCAP) Dr. Prem Pais, Dr. Denis Xavier 2009
23 Primary pREvention strategies at the community level to Promote treatment Adherence to pREvent cardiovascular disease (PREPARE) Dr. Prem Pais, Dr. Denis Xavier 2009
24 An observational study to determine predisposing conditions & regional variations in Atrial Fibrillation/flutter (RELY AF Registry) Dr. Prem Pais, Dr. Denis Xavier 2009
25 A randomized controlled trial of timing of Intervention (early versus delayed) in Acute Coronary Syndromes (TIMACS) Dr. Prem Pais, Dr. Denis Xavier 2009
26 A comparative study between standard and high dose of clopidogrel in patients with unstable angina or non-ST segment elevation myocardial infarction managed with an early invasive strategy (CURRENT / OASIS-7) Dr. Prem Pais, Dr. Denis Xavier 2009
27 Heart Outcomes Prevention Evaluation - 3 Study (HOPE-3) Dr. Prem Pais, Dr. Denis Xavier 2008
28 Prevention Regimen for Effectively avoiding Second Strokes: A double-blind, active and placebo controlled study of Aggrenox vs. clopidogrel, with and without Micardis (PRoFESS ) Dr. Prem Pais, Dr. Denis Xavier 2008
29 A study which evaluated the association of risk factors for Acute Myocardial Infarction in native South Asians, especially at younger ages, when compared with individuals from other countries (INTERHEART) Dr. Prem Pais 2007
30 A registry that examined the treatment patterns and outcome of Acute Coronary Syndrome patients with renal dysfunction (CREATE ACS Registry) Dr. Denis Xavier, Dr. Prem Pais 2007