Cardiovascular Diseases

Introduction

The cardiovascular health activities are in response to the growing burden of these diseases due to the social, demographic, epidemiologic and health care transitions that have led to cardiovascular diseases being the number one cause of death in the country.

The activities are dedicated to:

  • Providing a platform for cardiovascular health research that is relevant to resource-limited settings
  • Focusing on key individual determinants (tobacco, diet, physical activity and psychological factors) as well as underlying social determinants (‘causes of causes’)
  • Providing a robust training environment that will foster a new generation of scholars engaged in cardiovascular research
  • Enhancing the translation and dissemination of research findings among vulnerable populations
  • Achieving a reputation for excellence in cardiovascular health research

Sl No. Title Authors Journal Name Publication Year
1 Randomized, Double-Blind, Active Comparator Pharmacodynamic Study of Platelet Inhibition with Crushed and Integral Formulations of Clopidogrel and Ticagrelor in Acute Coronary Syndrome Harsha Teja Perla, Viji Samuel Thomson, Thomas V. Attumalil, Tulasi Geevar, Anoop George Alex, Rutvi G. Dave, Sukesh C. Nair, S. Mahasampath Gowri, Prem K. Mony, Paul George & George Joseph American Journal of Cardiovascular Drugs June 2023
2 Vitamin D supplementation and adverse skeletal and non-skeletal outcomes in individuals at increased cardiovascular risk: Results from the International Polycap Study (TIPS-3) P Joseph, *P Pais*, P Gao, K Teo, *D Xavier*, P Lopez-Jaramillo, K Yusoff, A Santoso, H Gamra, SH Talukder, S Yusuf et al…. Nutrition, Metabolism and Cardiovascular Diseases 2023
3 A randomized controlled trial evaluating a theory driven, complex intervention centered on task sharing and mobile health to improve selfcare and outcomes in heart failure – The PANACEA-HF RCT: Design and rationale *DY Kamath*, J Abdullakutty, BB Granger, S Kulkarni, *KB Bhuvana*, LJ Salazar, S Shifra, J Idiculla, J Narendra, K Varghese, *D Xavier*. Cardiology Research and Practice 2023
4 Characteristics, clinical practice patterns and outcomes of strokes in India: INSPIRE-A multicentre prospective study *Denis Xavier*, Robert Murphy, *Prem Pais*, Jeyaraj Pandian, Sarma RK Gosala, Nandini Mathur, Dheeraj Khurana, R Sundararajan, Rajeev Gupta, Rajnish Joshi, Somesh Vanchilingam, PN Venkatarathanamma, Soaham Desai, Catriona Reddin, Martin O'Donnell, Salim Yusuf. International Journal of Stroke 2023
5 POISE-3 Trial Investigators and Study Groups- ''Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery'' Maura Marcucci, Thomas W Painter, David Conen, Vladimir Lomivorotov, Daniel I Sessler, Matthew TV Chan, Flavia K Borges, Kate Leslie, Emmanuelle Duceppe, María José Martínez-Zapata, Chew Yin Wang, Denis Xavier, Sandra N Ofori, Michael Ke Wang, et al... Annals of Internal Medicine 2023
6 Sleep Patterns and the Risk of Acute Stroke: Results from the INTERSTROKE International Case-Control Study Christine Eileen Mc Carthy, Salim Yusuf, Conor Judge, Alberto Alvarez-Iglesias, Graeme J Hankey, Shahram Oveisgharan, Albertino Damasceno, Helle Klingenberg Iversen, Annika Rosengren, Alvaro Avezum, Patricio Lopez-Jaramillo, *Denis Xavier*, Xingyu Wang, Sumathy Rangarajan, Martin O'D”nnell Neurology 2023
7 Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study Robert P Murphy, Catriona Reddin, Annika Rosengren, Conor Judge, Graeme J Hankey, John Ferguson, Alberto Alvarez-Iglesias, Shahram Oveisgharan, Mohammad Wasay, Clodagh McDermott, Helle Klingenberg Iversen, Fernando Lanas, Fawaz Al-Hussain, Anna Czlonkowska, Aytekin Oguz, Adesola Ogunniyi, Albertino Damasceno, *Denis Xavier*, Alvaro Avezum, Xingyu Wang, Peter Langhorne, Salim Yusuf, Martin O'Donnell Neurology 2023
8 Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA) Jeyaraj Durai Pandian, Mahesh Pundlik Kate, Padmavathyamma Narayanapillai Sylaja, Dheeraj, *Prem Pais*, *Denis Xavier*, et al…. The Lancet Global Health 2023
9 Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease Johannes FE Mann, Philip Joseph, Peggy Gao, *Prem Pais*, Jessica Tyrwhitt, *Denis Xavier*, Salim Yusuf et al…. Kidney International 2023
10 Effects of a polypill, aspirin or both on cognitive and functional outcomes Bosch JJ, O’Donnel, Gao P, Joseph P, *Pais P*, *Xavier D*, Dans A, Lopez J & Yusuf S JAMA Neurology 2023
11 Diet, cardiovascular disease, and mortality in 80 countries Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan, Martin O’Donnell, Weihong Hu, Gilles Dagenais, Andreas Wielgosz, Scott A Lear, Li Wei, Rafael Diaz, Alvaro Avezum, Patricio Lopez-Jaramillo, Fernando Lanas, Sumathi Swaminathan, Manmeet Kaur, K Vijayakumar, Viswanathan Mohan, Rajeev Gupta, Andrzej Szuba, Romaina Iqbal, Rita Yusuf, Noushin Mohammadifard, Rasha Khatib, Nafiza Mat Nasir, Kubilay Karsidag, Annika Rosengren, Afzalhussein Yusufali, Edelweiss Wentzel-Viljoen, Jephat Chifamba, Antonio Dans, Khalid F Alhabib, Karen Yeates, Koon Teo, Hertzel C Gerstein, Salim Yusuf. European Heart Journal 2023
12 Cardiovascular disease, mortality, and their associations with modifiable risk factors in a multi-national South Asia cohort: a PURE substudy Philip Joseph, Vellappillil Raman Kutty, Viswanathan Mohan, Rajesh Kumar, Prem Mony, Krishnapillai Vijayakumar, Shofiqul Islam, Romaina Iqbal, Khawar Kazmi, Omar Rahman, Rita Yusuf, Ranjit Mohan Anjana, Indu Mohan, Sumathy Rangarajan, Rajeev Gupta and Salim Yusuf European Heart Journal 2022
13 Effects of Aspirin in Primary Prevention of Cardiovascular (CV) Disease in People with Chronic Kidney Disease (CKD): Results of the TIPS3 Trial. Johannes FE Mann, Philip Joseph, Peggy Gao, *Prem Pais*, *Denis Xavier*, Tony Dans, Patricio Lopez Jaramillo, Habib Gamra, Jessica Tyrwhitt, Salim Yusuf MO201 Nephrology Dialysis Transplantation 2022
14 Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study Smyth A, O’Donnell M, Hankey GJ, Rangarajan S, Lopez-Jaramillo P, *Xavier D*, Zhang H, Canavan M, Damasceno A, Langhorne P, Avezum A, INTERSTROKE investigators European Heart Journal 2022
15 Associations of unprocessed and processed meat intake with mortality and cardiovascular disease in 21 countries [Prospective Urban Rural Epidemiology (PURE) Study]: a prospective cohort study Romaina Iqbal, Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Andreas Wielgosz, Alvaro Avezum, Pamela Seron, Khalid F AlHabib, Patricio Lopez-Jaramillo, Sumathi Swaminathan, Noushin Mohammadifard, Katarzyna Zato?ska, Hu Bo, Ravi Prasad Varma, Omar Rahman, AfzalHussein Yusufali, Yin Lu, Noorhassim Ismail, Annika Rosengren, Ne?e Imeryuz, Karen Yeates, Jephat Chifamba, Antonio Dans, Rajesh Kumar, Liu Xiaoyun, Lungi Tsolekile, Rasha Khatib, Rafael Diaz, Koon Teo, Salim Yusuf. The American Journal of Clinical Nutrition 2021