Infectious Diseases

Introduction

The tuberculosis (TB) epidemiological studies were conducted at the Palamaner field site in Chittoor District, Andhra Pradesh, set up under a programme approved by the Ministry of Health Screening Committee, Government of India. The studies were funded by the Aeras Global TB Vaccine Foundation, USA, and the Research Council of Norway. Three large cohort studies assessed cumulative incidence of TB in 1) newborns followed for 2 years, 2) adolescents aged 12 to <18 years followed for 2 years and 3) household contacts of smear positive TB index cases followed for a year. Apart from epidemiological analyses, the studies will also contribute to the evaluation of biomarkers in latent TB infection and TB disease.

Sl No. Title Authors Journal Name Publication Year
16 Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy Hameed PS, Bharatham N, Katagihallimath N, Sharma S, Nandishaiah R, Shanbhag AP, Thomas T, Narjari R, Sarma M, Bhowmik P, Amar P, Ravishankar R, Jayaraman R, Muthan K, Subbiah R, Ramachandran V, Balasubramanian V, Datta S Sci Rep 2018
17 Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis Ahmed A, Adiga V, Nayak S, Uday Kumar JAJ, Dhar C, Sahoo PN, Sundararaj BK, Souza GD, Vyakarnam A PLoS Pathog 2018
18 Seasonal prevalence of antibiotic-resistant bacteria in the river Mula-Mutha, India Dhawde R, Macaden R, Ghadge A, Birdi T Environ Monit Assess 2018
19 Incidence of tuberculosis and the influence of surveillance strategy on tuberculosis case-finding and all-cause mortality: a cluster randomised trial in Indian neonates vaccinated with BCG Jenum S, Sumithra S, Nelson J, Christian R, Anneke C H, Vicky C, Esther L, Mark DT, Harleen M S G, Mario V BMJ Open Respir Res 2018
20 High Abundance of genus Prevotella in the gut of perinatally HIV-infected children is associated with IP-10 levels despite therapy Kaur US, Shet A, Rajnala N, Gopalan BP, Moar P, D H, Singh BP, Chaturvedi R, Tandon R Sci Rep 2018
21 Development of a Novel Tablet-based Approach to Reduce HIV Stigma among Healthcare Staff in India Radhakrishna K, Dass D, Raj T, Rakesh D, Kishore R, Srinivasan K, Nyblade L, Ekstrand-Abueg M, Ekstrand ML Perspect Health Inf Manag 2017
22 Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children Gjøen JE, Jenum S, Sivakumaran D, Mukherjee A, Macaden R, Kabra SK, Lodha R, Ottenhoff THM, Haks MC, Doherty TM, Ritz C, Grewal HMS Sci Rep 2017
23 Enhancing the sensitivity of Dengue virus serotype detection by RT-PCR among infected children in India Ahamed SF, Vivek R, Kotabagi S, Nayak K, Chandele A, Kaja MK, Shet A J Virol Methods 2017
24 Evaluation of a pan-serotype point-of-care rapid diagnostic assay for accurate detection of acute dengue infection Vivek R, Ahamed SF, Kotabagi S, Chandele A, Khanna I, Khanna N, Nayak K, Dias M, Kaja MK, Shet A Diagn Microbiol Infect Dis 2017
25 Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10+ Th17 CD4 T-cells differentiate latent from active tuberculosis Rakshit S, Adiga V, Nayak S, Sahoo PN, Sharma PK, van Meijgaarden KE, Uk J AJ, Dhar C, Souza GD, Finak G, De Rosa SC, Ottenhoff THM, Vyakarnam A Sci Rep 2017
26 Deep sequencing of near full-length HIV-1 genomes from plasma identifies circulating subtype C and infrequent occurrence of AC recombinant form in Southern India Alampalli SV, Thomson MM, Sampathkumar R, Sivaraman K, U K J AJ, Dhar C, D Souza G, Berry N, Vyakarnam A PLoS One 2017
27 Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status Yu EA, John SH, Tablante EC, King CA, Kenneth J, Russell DG, Mehta S PLoS One 2017
28 Unbiased Identification of Blood-based Biomarkers for Pulmonary Tuberculosis by Modeling and Mining Molecular Interaction Networks Sambarey A, Devaprasad A, Mohan A, Ahmed A, Nayak S, Swaminathan S, D'Souza G, Jesuraj A, Dhar C, Babu S, Vyakarnam A, Chandra N EBioMedicine 2017
29 Sub-therapeutic nevirapine concentration during antiretroviral treatment initiation among children living with HIV: Implications for therapeutic drug monitoring Gopalan BP, Mehta K, D'souza RR, Rajnala N, A K HK, Ramachandran G, Shet A PLoS One 2017
30 Added Value of IP-10 as a Read-Out of Mycobacterium tuberculosis: Specific Immunity in Young Children Jenum S, Dhanasekaran S, Ritz C, Macaden R, Doherty TM, Grewal HM; TB Trials Study Group Pediatr Infect Dis J 2016