Infectious Diseases


The tuberculosis (TB) epidemiological studies were conducted at the Palamaner field site in Chittoor District, Andhra Pradesh, set up under a programme approved by the Ministry of Health Screening Committee, Government of India. The studies were funded by the Aeras Global TB Vaccine Foundation, USA, and the Research Council of Norway. Three large cohort studies assessed cumulative incidence of TB in 1) newborns followed for 2 years, 2) adolescents aged 12 to <18 years followed for 2 years and 3) household contacts of smear positive TB index cases followed for a year. Apart from epidemiological analyses, the studies will also contribute to the evaluation of biomarkers in latent TB infection and TB disease.

Sl No. Project Title Project Lead Year
1 PK-HCQ Study PI: Dr. Denis Xavier; Dr. Bhuvana KB 2020 onwards
2 ACT Study - Anti-Coronavirus Therapies (ACT) to prevent progression of COVID-19: Randomized trials PI: Dr. Denis Xavier, Co-I: Dr. Prem Pais / Dr.Atiya Faruqui/ Dr. Bhuvana K B 2020
3 Prevalence survey of Plasmodium falciparum antimalarial drug resistance markers at sites in India Dr. Mary Dias 2018
4 Reagent Evaluation: Feasibility of Tuberculosis Diagnosis by Flow Cytometry Dr. Mary Dias 2018
5 Biomarker signatures for diagnosis for tuberculosis Dr. Mary Dias 2018
6 Study of cross-neutralization of flavivirus by dengue antibodies Dr. Anita Shet 2017
7 Establish a reference standard for HIV Screening with the use of ELISA from finger stick blood sampled on DBS filter paper Dr. Savitha Nagaraj, Dr. Tony Raj 2017
8 Sequence and analysis of Non-tuberculous Mycobacteria Dr. Ragini Macaden; Dr. Sutton Granger, JCVI (J Craig Venter Institute) USA 2016
9 Technology for TB: Mobile phone based directly observed treatment for supporting adherence to antitubercular treatment in South India Dr. Rashmi Rodrigues 2016
10 Influence of single versus multiple dengue serotype concurrent infections on clinical manifestations and the B-cell response Dr. Anita Shet 2015
11 A multicentric observational study to examine the replicative fitness and pathologic properties of the emerging new viral strain of HIV-1 in India Dr. Anita Shet 2015
12 DBT CoE HIV-TB Study Dr George D’Souza 2014
13 Wellcome Trust DBT Infectious Disease Project (Wellcome DBT-ID project) Dr. Anita Shet 2014
14 Validation of true lab molecular biology for diagnosis of hepatitis-B, salmonella and tuberculosis. Dr. John Kenneth 2013
15 Validation of true lab Micro Polymerase Chain Reaction for Diagnosis of tuberculosis and estimation of drug resistance. Dr John Kenneth 2013